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A fellow of IEEE, Sheu is currently active in research related to semantic computing, robotic computing, and complex biomedical systems. He has published two books, Intelligent Robotic Planning Systems, and Software Engineering and Environment - An Object-Oriented Perspective, and he is a co-editor of Semantic Computing (IEEE Press/Wiley). He also has published extensively in object-relational data and knowledge engineering, semantic computing, robotic computing, and biomedical computing. He is the founder of the Institute for Semantic Computing and Robotic Computing (SC-RC), the IEEE International Conference of Semantic Computing (ICSC), the IEEE Computer Society Technical Committee on Semantic Computing (TCSEM), and the Knowledge Societies, an accredited member of UNESCO/USFUCA. He is the founding editor-in-chief of the International Journal of Semantic Computing (IJSC) and the forthcoming Encyclopedia with Semantic Computing (ESC), and a co-founder of the IEEE International Conference of Multimedia Big Data (BigMM), the IEEE International Conference on Robotic Computing (ICRC), and the Bay Area Multimedia Forum (BAMMF).

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